Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model

BACKGROUND: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservation present in these protein sequences presumably are due to selective constraints maintaining important but unknown struc...

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Detalhes bibliográficos

Publicado no:	BMC Bioinformatics
Principais autores:	Neuwald, Andrew F, Liu, Jun S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2004
Assuntos:	Methodology Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15504234/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2105-5-157
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