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Inferring joint sequence-structural determinants of protein functional specificity

Residues responsible for allostery, cooperativity, and other subtle but functionally important interactions remain difficult to detect. To aid such detection, we employ statistical inference based on the assumption that residues distinguishing a protein subgroup from evolutionarily divergent subgrou...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Neuwald, Andrew F, Aravind, L, Altschul, Stephen F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770160/
https://ncbi.nlm.nih.gov/pubmed/29336305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29880
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