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Inferring joint sequence-structural determinants of protein functional specificity
Residues responsible for allostery, cooperativity, and other subtle but functionally important interactions remain difficult to detect. To aid such detection, we employ statistical inference based on the assumption that residues distinguishing a protein subgroup from evolutionarily divergent subgrou...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5770160/ https://ncbi.nlm.nih.gov/pubmed/29336305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29880 |
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