Deep Analysis of Residue Constraints (DARC): identifying determinants of protein functional specificity

Protein functional constraints are manifest as superfamily and functional-subgroup conserved residues, and as pairwise correlations. Deep Analysis of Residue Constraints (DARC) aids the visualization of these constraints, characterizes how they correlate with each other and with structure, and estim...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tondnevis, Farzaneh, Dudenhausen, Elizabeth E., Miller, Andrew M., McKenna, Robert, Altschul, Stephen F., Bloom, Linda B., Neuwald, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997377/
https://ncbi.nlm.nih.gov/pubmed/32015389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55118-6
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