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Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice
To further evaluate the parameters whereby intracerebral administration of recombinant α-synuclein (αS) induces pathological phenotypes in mice, we conducted a series of studies where αS fibrils were injected into the brains of M83 (A53T) and M47 (E46K) αS transgenic (Tg) mice, and non-transgenic (n...
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| Publicado en: | Acta Neuropathol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869357/ https://ncbi.nlm.nih.gov/pubmed/24659240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1268-0 |
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