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Polarized localization of voltage-gated Na(+) channels is regulated by concerted FGF13 and FGF14 action

Clustering of voltage-gated sodium channels (VGSCs) within the neuronal axon initial segment (AIS) is critical for efficient action potential initiation. Although initially inserted into both somatodendritic and axonal membranes, VGSCs are concentrated within the axon through mechanisms that include...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Pablo, Juan Lorenzo, Wang, Chaojian, Presby, Matthew M., Pitt, Geoffrey S.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868475/
https://ncbi.nlm.nih.gov/pubmed/27044086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521194113
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