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Voltage-Gated Calcium Channels in Nonexcitable Tissues

The identification of a gain-of-function mutation in CACNA1C as the cause of Timothy syndrome, a rare disorder characterized by cardiac arrhythmias and syndactyly, highlighted roles for the L-type voltage-gated Ca(2+) channel Ca(V)1.2 in nonexcitable cells. Previous studies in cells and animal model...

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Détails bibliographiques
Publié dans:Annu Rev Physiol
Auteurs principaux: Pitt, Geoffrey S., Matsui, Maiko, Cao, Chike
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281591/
https://ncbi.nlm.nih.gov/pubmed/33106102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-031620-091043
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