Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic

Protein–protein interactions (PPI) offer unexploited opportunities for CNS drug discovery and neurochemical probe development. Here, we present ZL181, a novel peptidomimetic targeting the PPI interface of the voltage-gated Na(+) channel Nav1.6 and its regulatory protein fibroblast growth factor 14 (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Ali, Syed R., Liu, Zhiqing, Nenov, Miroslav N., Folorunso, Oluwarotimi, Singh, Aditya, Scala, Federico, Chen, Haiying, James, T. F., Alshammari, Musaad, Panova-Elektronova, Neli I., White, Mark Andrew, Zhou, Jia, Laezza, Fernanda
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033619/
https://ncbi.nlm.nih.gov/pubmed/29359916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00399
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados