CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability

Recent data shows that fibroblast growth factor 14 (FGF14) binds to and controls the function of the voltage-gated sodium (Nav) channel with phenotypic outcomes on neuronal excitability. Mutations in the FGF14 gene in humans have been associated with brain disorders that are partially recapitulated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Hsu, Wei-Chun J., Scala, Federico, Nenov, Miroslav N., Wildburger, Norelle C., Elferink, Hannah, Singh, Aditya K., Chesson, Charles B., Buzhdygan, Tetyana, Sohail, Maveen, Shavkunov, Alexander S., Panova, Neli I., Nilsson, Carol L., Rudra, Jai S., Lichti, Cheryl F., Laezza, Fernanda
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871802/
https://ncbi.nlm.nih.gov/pubmed/26917740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500161
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