CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability

Recent data shows that fibroblast growth factor 14 (FGF14) binds to and controls the function of the voltage-gated sodium (Nav) channel with phenotypic outcomes on neuronal excitability. Mutations in the FGF14 gene in humans have been associated with brain disorders that are partially recapitulated...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Hsu, Wei-Chun J., Scala, Federico, Nenov, Miroslav N., Wildburger, Norelle C., Elferink, Hannah, Singh, Aditya K., Chesson, Charles B., Buzhdygan, Tetyana, Sohail, Maveen, Shavkunov, Alexander S., Panova, Neli I., Nilsson, Carol L., Rudra, Jai S., Lichti, Cheryl F., Laezza, Fernanda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871802/
https://ncbi.nlm.nih.gov/pubmed/26917740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500161
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi