CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability

Recent data shows that fibroblast growth factor 14 (FGF14) binds to and controls the function of the voltage-gated sodium (Nav) channel with phenotypic outcomes on neuronal excitability. Mutations in the FGF14 gene in humans have been associated with brain disorders that are partially recapitulated...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Hsu, Wei-Chun J., Scala, Federico, Nenov, Miroslav N., Wildburger, Norelle C., Elferink, Hannah, Singh, Aditya K., Chesson, Charles B., Buzhdygan, Tetyana, Sohail, Maveen, Shavkunov, Alexander S., Panova, Neli I., Nilsson, Carol L., Rudra, Jai S., Lichti, Cheryl F., Laezza, Fernanda
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871802/
https://ncbi.nlm.nih.gov/pubmed/26917740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500161
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