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FGF14 regulates presynaptic Ca(2+) channels and synaptic transmission
Fibroblast growth factor homologous factors (FHFs) are not growth factors, but instead bind to voltage-gated Na(+) channels (Na(V)) and regulate their function. Mutations in FGF14, a FHF that is the locus for spinocerebellar ataxia 27 (SCA27) are believed pathogenic because of a dominant-negative re...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736584/ https://ncbi.nlm.nih.gov/pubmed/23831029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.012 |
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