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FGF14 regulates presynaptic Ca(2+) channels and synaptic transmission

Fibroblast growth factor homologous factors (FHFs) are not growth factors, but instead bind to voltage-gated Na(+) channels (Na(V)) and regulate their function. Mutations in FGF14, a FHF that is the locus for spinocerebellar ataxia 27 (SCA27) are believed pathogenic because of a dominant-negative re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yan, Haidun, Pablo, Juan L., Pitt, Geoffrey S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736584/
https://ncbi.nlm.nih.gov/pubmed/23831029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.012
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