A TRPV Channel in Drosophila Motor Neurons Regulates Presynaptic Resting Ca(2+) Levels, Synapse Growth, and Synaptic Transmission

Presynaptic resting Ca(2+) influences synaptic vesicle (SV) release probability. Here, we report that a TRPV channel, Inactive (Iav), maintains presynaptic resting [Ca(2+)] by promoting Ca(2+) release from the endoplasmic reticulum in Drosophila motor neurons, and is required for both synapse develo...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Wong, Ching-On, Chen, Kuchuan, Lin, Yong Qi, Chao, Yufang, Duraine, Lita, Lu, Zhongmin, Yoon, Wan Hee, Sullivan, Jeremy M., Broadhead, Geoffrey T., Sumner, Charlotte J., Lloyd, Thomas E., Macleod, Gregory T., Bellen, Hugo J., Venkatachalam, Kartik
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254599/
https://ncbi.nlm.nih.gov/pubmed/25451193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.09.030
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