A TRPV Channel in Drosophila Motor Neurons Regulates Presynaptic Resting Ca(2+) Levels, Synapse Growth, and Synaptic Transmission

Presynaptic resting Ca(2+) influences synaptic vesicle (SV) release probability. Here, we report that a TRPV channel, Inactive (Iav), maintains presynaptic resting [Ca(2+)] by promoting Ca(2+) release from the endoplasmic reticulum in Drosophila motor neurons, and is required for both synapse develo...

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Detaylı Bibliyografya
Yayımlandı:Neuron
Asıl Yazarlar: Wong, Ching-On, Chen, Kuchuan, Lin, Yong Qi, Chao, Yufang, Duraine, Lita, Lu, Zhongmin, Yoon, Wan Hee, Sullivan, Jeremy M., Broadhead, Geoffrey T., Sumner, Charlotte J., Lloyd, Thomas E., Macleod, Gregory T., Bellen, Hugo J., Venkatachalam, Kartik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254599/
https://ncbi.nlm.nih.gov/pubmed/25451193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.09.030
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