The FGF14(F145S) Mutation Disrupts the Interaction of FGF14 with Voltage-Gated Na(+) Channels and Impairs Neuronal Excitability

Fibroblast growth factor 14 (FGF14) belongs to the intracellular FGF homologous factor subfamily of FGF proteins (iFGFs) that are not secreted and do not activate tyrosine kinase receptors. The iFGFs, however, have been shown to interact with the pore-forming (α) subunits of voltage-gated Na(+) (Na(...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Laezza, Fernanda, Gerber, Benjamin R., Lou, Jun-Yang, Kozel, Marie A., Hartman, Hali, Marie Craig, Ann, Ornitz, David M., Nerbonne, Jeanne M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673376/
https://ncbi.nlm.nih.gov/pubmed/17978045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2282-07.2007
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