Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib

Although sorafenib is expected to have a chemopreventive effect on hepatocellular carcinoma (HCC) recurrence, there are limitations to its use because of adverse effects, including effects on liver function. We have reported that the iron chelator, deferoxamine can prevent liver fibrosis and preneop...

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Foilsithe in:J Clin Biochem Nutr
Main Authors: Yamamoto, Naoki, Yamasaki, Takahiro, Takami, Taro, Uchida, Koichi, Fujisawa, Koichi, Matsumoto, Toshihiko, Saeki, Issei, Terai, Shuji, Sakaida, Isao
Formáid: Artigo
Teanga:Inglês
Foilsithe: the Society for Free Radical Research Japan 2016
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865599/
https://ncbi.nlm.nih.gov/pubmed/27257345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.15-127
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