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Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib

Although sorafenib is expected to have a chemopreventive effect on hepatocellular carcinoma (HCC) recurrence, there are limitations to its use because of adverse effects, including effects on liver function. We have reported that the iron chelator, deferoxamine can prevent liver fibrosis and preneop...

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Bibliografski detalji
Izdano u:J Clin Biochem Nutr
Glavni autori: Yamamoto, Naoki, Yamasaki, Takahiro, Takami, Taro, Uchida, Koichi, Fujisawa, Koichi, Matsumoto, Toshihiko, Saeki, Issei, Terai, Shuji, Sakaida, Isao
Format: Artigo
Jezik:Inglês
Izdano: the Society for Free Radical Research Japan 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865599/
https://ncbi.nlm.nih.gov/pubmed/27257345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.15-127
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