Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib

Although sorafenib is expected to have a chemopreventive effect on hepatocellular carcinoma (HCC) recurrence, there are limitations to its use because of adverse effects, including effects on liver function. We have reported that the iron chelator, deferoxamine can prevent liver fibrosis and preneop...

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Detalhes bibliográficos
Publicado no:J Clin Biochem Nutr
Main Authors: Yamamoto, Naoki, Yamasaki, Takahiro, Takami, Taro, Uchida, Koichi, Fujisawa, Koichi, Matsumoto, Toshihiko, Saeki, Issei, Terai, Shuji, Sakaida, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865599/
https://ncbi.nlm.nih.gov/pubmed/27257345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.15-127
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