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Deferasirox, an oral iron chelator, with gemcitabine synergistically inhibits pancreatic cancer cell growth in vitro and in vivo

OBJECTIVES: Iron is an essential element for cell proliferation and growth processes. We have reported that deferasirox (DFX), an oral iron chelator, showed antiproliferative activity against pancreatic cancer cells. This study aimed to elucidate the effects of combination of gemcitabine (GEM), stan...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Shinoda, Shuhei, Kaino, Seiji, Amano, Shogo, Harima, Hirofumi, Matsumoto, Toshihiko, Fujisawa, Koichi, Takami, Taro, Yamamoto, Naoki, Yamasaki, Takahiro, Sakaida, Isao
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033369/
https://ncbi.nlm.nih.gov/pubmed/29983871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25421
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