Deferasirox, an oral iron chelator, with gemcitabine synergistically inhibits pancreatic cancer cell growth in vitro and in vivo

OBJECTIVES: Iron is an essential element for cell proliferation and growth processes. We have reported that deferasirox (DFX), an oral iron chelator, showed antiproliferative activity against pancreatic cancer cells. This study aimed to elucidate the effects of combination of gemcitabine (GEM), stan...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Shinoda, Shuhei, Kaino, Seiji, Amano, Shogo, Harima, Hirofumi, Matsumoto, Toshihiko, Fujisawa, Koichi, Takami, Taro, Yamamoto, Naoki, Yamasaki, Takahiro, Sakaida, Isao
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033369/
https://ncbi.nlm.nih.gov/pubmed/29983871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25421
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