Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy

Experimental and clinical studies have indicated that the antileprosy drug clofazimine may contribute treatment-shortening activity when included in tuberculosis treatment regimens. Clofazimine accumulates to high levels in tissues, has a long half-life, and remains in the body for months after admi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Swanson, Rosemary V., Ammerman, Nicole C., Ngcobo, Bongani, Adamson, John, Moodley, Chivonne, Dorasamy, Afton, Moodley, Sashen, Mgaga, Zinhle, Bester, Linda A., Singh, Sanil D., Almeida, Deepak V., Grosset, Jacques H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862514/
https://ncbi.nlm.nih.gov/pubmed/26926638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00177-16
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados