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Pharmacokinetics and Pharmacodynamics of Clofazimine in a Mouse Model of Tuberculosis

The antileprosy drug clofazimine has shown potential for shortening tuberculosis treatment; however, the current dosing of the drug is not evidence based, and the optimal dosing is unknown. Our objective was to conduct a preclinical evaluation of the pharmacokinetics and pharmacodynamics of clofazim...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Swanson, Rosemary V., Adamson, John, Moodley, Chivonne, Ngcobo, Bongani, Ammerman, Nicole C., Dorasamy, Afton, Moodley, Sashen, Mgaga, Zinhle, Tapley, Asa, Bester, Linda A., Singh, Sanil, Grosset, Jacques H., Almeida, Deepak V.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432183/
https://ncbi.nlm.nih.gov/pubmed/25753644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00260-15
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