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Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates
Glutathione plays a central role in maintaining cellular redox homeostasis, and modulations to this status may affect malaria parasite sensitivity to certain types of antimalarials. In this study, we demonstrate that inhibition of glutathione biosynthesis in the Plasmodium berghei ANKA strain throug...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862499/ https://ncbi.nlm.nih.gov/pubmed/26953195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01836-15 |
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