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Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates
Glutathione plays a central role in maintaining cellular redox homeostasis, and modulations to this status may affect malaria parasite sensitivity to certain types of antimalarials. In this study, we demonstrate that inhibition of glutathione biosynthesis in the Plasmodium berghei ANKA strain throug...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862499/ https://ncbi.nlm.nih.gov/pubmed/26953195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01836-15 |
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