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Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates

Glutathione plays a central role in maintaining cellular redox homeostasis, and modulations to this status may affect malaria parasite sensitivity to certain types of antimalarials. In this study, we demonstrate that inhibition of glutathione biosynthesis in the Plasmodium berghei ANKA strain throug...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Songsungthong, Warangkhana, Koonyosying, Pongpisid, Uthaipibull, Chairat, Kamchonwongpaisan, Sumalee
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862499/
https://ncbi.nlm.nih.gov/pubmed/26953195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01836-15
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