Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model

BACKGROUND: The prevalence of drug resistance amongst the human malaria Plasmodium species has most commonly been associated with genomic mutation within the parasites. This phenomenon necessitates evolutionary predictive studies of possible resistance mutations, which may occur when a new drug is i...

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Detaylı Bibliyografya
Asıl Yazarlar: Tipsuwan, Wachiraporn, Srichairatanakool, Somdet, Kamchonwongpaisan, Sumalee, Yuthavong, Yongyuth, Uthaipibull, Chairat
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100258/
https://ncbi.nlm.nih.gov/pubmed/21554743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-119
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