Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates

Glutathione plays a central role in maintaining cellular redox homeostasis, and modulations to this status may affect malaria parasite sensitivity to certain types of antimalarials. In this study, we demonstrate that inhibition of glutathione biosynthesis in the Plasmodium berghei ANKA strain throug...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Songsungthong, Warangkhana, Koonyosying, Pongpisid, Uthaipibull, Chairat, Kamchonwongpaisan, Sumalee
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Susceptibility
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862499/
https://ncbi.nlm.nih.gov/pubmed/26953195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01836-15
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