Role of the Cys154Arg Substitution in Ribosomal Protein L3 in Oxazolidinone Resistance in Mycobacterium tuberculosis

We expressed the wild-type rplC and mutated rplC (Cys154Arg) genes, respectively, in Mycobacterium tuberculosis H37Ra and H37Rv in an attempt to delineate the role of rplC (Cys154Arg) regarding oxazolidinone resistance. An increase of the MICs of linezolid (LZD) and sutezolid (PNU-100480, PNU) again...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Makafe, Gaëlle Guiewi, Cao, Yuanyuan, Tan, Yaoju, Julius, Mugweru, Liu, Zhiyong, Wang, Changwei, Njire, Moses M., Cai, Xingshan, Liu, Tianzhou, Wang, Bangxing, Pang, Wei, Tan, Shouyong, Zhang, Buchang, Yew, Wing Wai, Lamichhane, Gyanu, Guo, Jintao, Zhang, Tianyu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862453/
https://ncbi.nlm.nih.gov/pubmed/26953211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00152-16
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items