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Identification of side- and shear-dependent microRNAs regulating porcine aortic valve pathogenesis

Aortic valve (AV) calcification is an inflammation driven process that occurs preferentially in the fibrosa. To explore the underlying mechanisms, we investigated if key microRNAs (miRNA) in the AV are differentially expressed due to disturbed blood flow (oscillatory shear (OS)) experienced by the f...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Rathan, Swetha, Ankeny, Casey J., Arjunon, Sivakkumar, Ferdous, Zannatul, Kumar, Sandeep, Fernandez Esmerats, Joan, Heath, Jack M., Nerem, Robert M., Yoganathan, Ajit P., Jo, Hanjoong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858741/
https://ncbi.nlm.nih.gov/pubmed/27151744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25397
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