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Identification of side- and shear-dependent microRNAs regulating porcine aortic valve pathogenesis

Aortic valve (AV) calcification is an inflammation driven process that occurs preferentially in the fibrosa. To explore the underlying mechanisms, we investigated if key microRNAs (miRNA) in the AV are differentially expressed due to disturbed blood flow (oscillatory shear (OS)) experienced by the f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rathan, Swetha, Ankeny, Casey J., Arjunon, Sivakkumar, Ferdous, Zannatul, Kumar, Sandeep, Fernandez Esmerats, Joan, Heath, Jack M., Nerem, Robert M., Yoganathan, Ajit P., Jo, Hanjoong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858741/
https://ncbi.nlm.nih.gov/pubmed/27151744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25397
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