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Discovery of shear- and side-specific mRNAs and miRNAs in human aortic valvular endothelial cells
The role of endothelial cells (ECs) in aortic valve (AV) disease remains relatively unknown; however, disease preferentially occurs in the fibrosa. We hypothesized oscillatory shear (OS) present on the fibrosa stimulates ECs to modify mRNAs and microRNAs (miRNAs) inducing disease. Our goal was to id...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191100/ https://ncbi.nlm.nih.gov/pubmed/21705672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00117.2011 |
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