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Shear-Sensitive Genes in Aortic Valve Endothelium

Significance: Currently, calcific aortic valve disease (CAVD) is only treatable through surgical intervention because the specific mechanisms leading to the disease remain unclear. In this review, we explore the forces and structure of the valve, as well as the mechanosensors and downstream signalin...

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Détails bibliographiques
Publié dans:Antioxid Redox Signal
Auteurs principaux: Fernández Esmerats, Joan, Heath, Jack, Jo, Hanjoong
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011632/
https://ncbi.nlm.nih.gov/pubmed/26651130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6554
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