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Shear-Sensitive Genes in Aortic Valve Endothelium

Significance: Currently, calcific aortic valve disease (CAVD) is only treatable through surgical intervention because the specific mechanisms leading to the disease remain unclear. In this review, we explore the forces and structure of the valve, as well as the mechanosensors and downstream signalin...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Fernández Esmerats, Joan, Heath, Jack, Jo, Hanjoong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011632/
https://ncbi.nlm.nih.gov/pubmed/26651130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6554
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