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mTORC2 critically regulates renal potassium handling
The mTOR pathway orchestrates cellular homeostasis. The rapamycin-sensitive mTOR complex (mTORC1) in the kidney has been widely studied; however, mTORC2 function in renal tubules is poorly characterized. Here, we generated mice lacking mTORC2 in the distal tubule (Rictor(fl/fl) Ksp-Cre mice), which...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855939/ https://ncbi.nlm.nih.gov/pubmed/27043284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80304 |
| תגים: |
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