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mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation

Mammalian target of rapamycin (mTOR), a regulator of growth in many tissues, mediates its activity through two multiprotein complexes, mTORC1 or mTORC2. The role of mTOR signalling in skin morphogenesis and epidermal development is unknown. Here we identify mTOR as an essential regulator in skin mor...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Ding, Xiaolei, Bloch, Wilhelm, Iden, Sandra, Rüegg, Markus A., Hall, Michael N., Leptin, Maria, Partridge, Linda, Eming, Sabine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095294/
https://ncbi.nlm.nih.gov/pubmed/27807348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13226
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