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In vivo evidence for mTORC2-mediated actin cytoskeleton rearrangement in neurons

The mammalian target of rapamycin (mTOR) assembles into two distinct multi-protein complexes called mTORC1 and mTORC2. While mTORC1 controls the signaling pathways important for cell growth, the physiological function of mTORC2 is only partially known. Here we comment on recent work on gene-targeted...

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Hlavní autoři: Angliker, Nico, Rüegg, Markus A
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201605/
https://ncbi.nlm.nih.gov/pubmed/24721730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioa.26497
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