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Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology
The mammalian target of rapamycin (mTOR) assembles into two distinct multi-protein complexes called mTORC1 and mTORC2. Whereas mTORC1 is known to regulate cell and organismal growth, the role of mTORC2 is less understood. We describe two mouse lines that are devoid of the mTORC2 component rictor in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628512/ https://ncbi.nlm.nih.gov/pubmed/23569215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205030 |
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