mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

Mammalian target of rapamycin complex 1 (mTORC1) is a key regulator of cell metabolism and autophagy. Despite widespread clinical use of mTORC1 inhibitors, the role of mTORC1 in renal tubular function and kidney homeostasis remains elusive. By using constitutive and inducible deletion of conditional...

詳細記述

保存先:
書誌詳細
主要な著者: Grahammer, Florian, Haenisch, Nora, Steinhardt, Frederic, Sandner, Lukas, Roerden, Malte, Arnold, Frederic, Cordts, Tomke, Wanner, Nicola, Reichardt, Wilfried, Kerjaschki, Dontscho, Ruegg, Markus A., Hall, Michael N., Moulin, Pierre, Busch, Hauke, Boerries, Melanie, Walz, Gerd, Artunc, Ferruh, Huber, Tobias B.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
PNAS Plus
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103333/
https://ncbi.nlm.nih.gov/pubmed/24958889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402352111
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