The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers

Benzo[a]pyrene (BaP) is a human carcinogen that covalently binds to DNA after metabolic activation by cytochrome P450 (CYP) enzymes. In this study human recombinant CYPs (CYP1A1, 1A2, 1B1, 2A6, 2B6, 2C8, 2C9, 2C19, 2E1, 3A4, and 3A5) were expressed in Supersomes™ together with their reductases, NADP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Environ Mol Mutagen
Päätekijät: Šulc, Miroslav, Indra, Radek, Moserová, Michaela, Schmeiser, Heinz H., Frei, Eva, Arlt, Volker M., Stiborová, Marie, White, P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Brief Communications
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855618/
https://ncbi.nlm.nih.gov/pubmed/26919089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22001
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia