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Dok-1 Negatively Regulates Platelet Integrin αIIbβ3 Outside-in Signaling and Inhibits Thrombosis in Mice
Adaptor proteins play a critical role in the assembly of signaling complexes after engagement of platelet receptors by agonists such as collagen, ADP and thrombin. Recently, using proteomics, the Dok (downstream of tyrosine kinase) adapter proteins were identified in human and mouse platelets. In vi...
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| Publicat a: | Thromb Haemost |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854776/ https://ncbi.nlm.nih.gov/pubmed/26790499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH15-05-0373 |
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