NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis

In addition to their hemostatic function, platelets play an important role in regulating the inflammatory response. The platelet NLRP3 inflammasome not only promotes interleukin-1β secretion, but was also found to be upregulated during platelet activation and thrombus formation in vitro. However, th...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Qiao, Jianlin, Wu, Xiaoqing, Luo, Qi, Wei, Guangyu, Xu, Mengdi, Wu, Yulu, Liu, Yun, Li, Xiaoqian, Zi, Jie, Ju, Wen, Fu, Lin, Chen, Chong, Wu, Qingyun, Zhu, Shengyun, Qi, Kunming, Li, Depeng, Li, Zhenyu, Andrews, Robert K., Zeng, Lingyu, Gardiner, Elizabeth E., Xu, Kailin
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119128/
https://ncbi.nlm.nih.gov/pubmed/29794149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.191700
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