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Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice
The capacity of pancreatic β cells to maintain glucose homeostasis during chronic physiologic and immunologic stress is important for cellular and metabolic homeostasis. Insulin receptor substrate 2 (IRS2) is a regulated adapter protein that links the insulin and IGF1 receptors to downstream signali...
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| I publikationen: | JCI Insight |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854304/ https://ncbi.nlm.nih.gov/pubmed/27152363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.80749 |
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