Wordt geladen...
Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion
DNA polymerase γ (pol γ) is the sole DNA polymerase devoted to mitochondrial DNA (mtDNA) replication. We have characterized the molecular and physiological effects of over-expression of the catalytic subunit of pol γ, pol γ-α, in the nervous system of Drosophila melanogaster using the upstream activ...
Bewaard in:
| Gepubliceerd in: | J Neurochem |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2007
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4853903/ https://ncbi.nlm.nih.gov/pubmed/17999718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.05122.x |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|