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Inhibiting DNA methylation switches adipogenesis to osteoblastogenesis by activating Wnt10a

Both adipocytes and osteoblasts share the mesodermal lineage that derives from mesenchymal stem cells. Most studies investigating the mechanisms underlying the regulation of adipogenic or osteoblastogenic development focus on transcriptional pathways; little is known about the epigenetic mechanisms...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Chen, Yii-Shyuan, Wu, Rui, Yang, Xiaosong, Kou, Shuping, MacDougald, Ormond A., Yu, Liqing, Shi, Hang, Xue, Bingzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853709/
https://ncbi.nlm.nih.gov/pubmed/27136753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25283
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