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Inhibiting DNA methylation switches adipogenesis to osteoblastogenesis by activating Wnt10a
Both adipocytes and osteoblasts share the mesodermal lineage that derives from mesenchymal stem cells. Most studies investigating the mechanisms underlying the regulation of adipogenic or osteoblastogenic development focus on transcriptional pathways; little is known about the epigenetic mechanisms...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4853709/ https://ncbi.nlm.nih.gov/pubmed/27136753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25283 |
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