Regulation of Cyclin D1 and Wnt10b Gene Expression by cAMP-responsive Element-binding Protein during Early Adipogenesis Involves Differential Promoter Methylation

Cyclin D1 expression is elevated and Wnt10b is repressed by cAMP during the first few hours of adipogenesis. cAMP-responsive element-binding protein (CREB) is a primary target for cAMP signaling, and we have shown that activation of CREB promotes adipogenesis and adipocyte survival. Here we tested t...

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Hlavní autoři: Fox, Keith E., Colton, Lillester A., Erickson, Paul F., Friedman, Jacob E., Cha, Hyuk C., Keller, Pernille, MacDougald, Ormond A., Klemm, Dwight J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Transcription, Chromatin, and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596384/
https://ncbi.nlm.nih.gov/pubmed/18957421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806423200
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