Inhibiting DNA methylation switches adipogenesis to osteoblastogenesis by activating Wnt10a

Both adipocytes and osteoblasts share the mesodermal lineage that derives from mesenchymal stem cells. Most studies investigating the mechanisms underlying the regulation of adipogenic or osteoblastogenic development focus on transcriptional pathways; little is known about the epigenetic mechanisms...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Chen, Yii-Shyuan, Wu, Rui, Yang, Xiaosong, Kou, Shuping, MacDougald, Ormond A., Yu, Liqing, Shi, Hang, Xue, Bingzhong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853709/
https://ncbi.nlm.nih.gov/pubmed/27136753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25283
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