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Inhibiting DNA methylation switches adipogenesis to osteoblastogenesis by activating Wnt10a

Both adipocytes and osteoblasts share the mesodermal lineage that derives from mesenchymal stem cells. Most studies investigating the mechanisms underlying the regulation of adipogenic or osteoblastogenic development focus on transcriptional pathways; little is known about the epigenetic mechanisms...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Chen, Yii-Shyuan, Wu, Rui, Yang, Xiaosong, Kou, Shuping, MacDougald, Ormond A., Yu, Liqing, Shi, Hang, Xue, Bingzhong
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853709/
https://ncbi.nlm.nih.gov/pubmed/27136753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25283
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