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Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression
Oxidized low-density lipoprotein (oxLDL) accumulates early in atherosclerosis and promotes endothelial nuclear factor κB (NF-κB) activation, proinflammatory gene expression and monocyte adhesion. Like for other atherogenic factors, oxLDL-induced proinflammatory responses requires integrin-dependent...
Guardat en:
| Publicat a: | J Cell Sci |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists Ltd
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852771/ https://ncbi.nlm.nih.gov/pubmed/26906414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.182097 |
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