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α5β1 Integrin Signaling Mediates Oxidized LDL-Induced Inflammation and Early Atherosclerosis

OBJECTIVE: Endothelial cell activation drives early atherosclerotic plaque formation. Both fibronectin deposition and accumulation of oxidized LDL (oxLDL) occur early during atherogenesis and both are implicated in enhanced endothelial cell activation. However, interplay between these responses has...

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Detalhes bibliográficos
Main Authors: Yurdagul, Arif, Green, Jonette, Albert, Patrick, McInnis, Marshall C., Mazar, Andrew P., Orr, A. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096780/
https://ncbi.nlm.nih.gov/pubmed/24833794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.303863
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