αvβ3 Integrins Mediate Flow-Induced NF-κB Activation, Proinflammatory Gene Expression, and Early Atherogenic Inflammation

Endothelial cell interactions with transitional matrix proteins, such as fibronectin, occur early during atherogenesis and regulate shear stress-induced endothelial cell activation. Multiple endothelial cell integrins bind transitional matrix proteins, including α5β1, αvβ3, and αvβ5. However, the ro...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Chen, Jie, Green, Jonette, Yurdagul, Arif, Albert, Patrick, McInnis, Marshall C., Orr, A. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597278/
https://ncbi.nlm.nih.gov/pubmed/26212910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.05.013
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