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Altered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flow
Shear stress generated by distinct blood flow patterns modulates endothelial cell phenotype to spatially restrict atherosclerotic plaque development. Signaling through p21-activated kinase (PAK) mediates several of the deleterious effects of shear stress, including enhanced NF-κB activation and proi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564533/ https://ncbi.nlm.nih.gov/pubmed/23171552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0513 |
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