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SAAFEC: Predicting the Effect of Single Point Mutations on Protein Folding Free Energy Using a Knowledge-Modified MM/PBSA Approach

Folding free energy is an important biophysical characteristic of proteins that reflects the overall stability of the 3D structure of macromolecules. Changes in the amino acid sequence, naturally occurring or made in vitro, may affect the stability of the corresponding protein and thus could be asso...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Getov, Ivan, Petukh, Marharyta, Alexov, Emil
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848968/
https://ncbi.nlm.nih.gov/pubmed/27070572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040512
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