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Predicting folding free energy changes upon single point mutations
Motivation: The folding free energy is an important characteristic of proteins stability and is directly related to protein's wild-type function. The changes of protein's stability due to naturally occurring mutations, missense mutations, are typically causing diseases. Single point mutati...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289912/ https://ncbi.nlm.nih.gov/pubmed/22238268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts005 |
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