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Predicting folding free energy changes upon single point mutations

Motivation: The folding free energy is an important characteristic of proteins stability and is directly related to protein's wild-type function. The changes of protein's stability due to naturally occurring mutations, missense mutations, are typically causing diseases. Single point mutati...

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Detalhes bibliográficos
Main Authors: Zhang, Zhe, Wang, Lin, Gao, Yang, Zhang, Jie, Zhenirovskyy, Maxim, Alexov, Emil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289912/
https://ncbi.nlm.nih.gov/pubmed/22238268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts005
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